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Identification of tumor-intrinsic drivers of immune exclusion in acral melanoma

Acral melanoma (AM) has distinct characteristics as compared with cutaneous melanoma and exhibits poor response to immune checkpoint inhibitors (ICIs). Tumor-intrinsic mechanisms of immune exclusion have been identified in many cancers but less studied in AM. We characterized clinically annotated tu...

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Detalles Bibliográficos
Autores principales: Augustin, Ryan C, Newman, Sarah, Li, Aofei, Joy, Marion, Lyons, Maureen, Pham, Mary P, Lucas, Peter, Smith, Katelyn, Sander, Cindy, Isett, Brian, Davar, Diwakar, Najjar, Yana G, Zarour, Hassane M, Kirkwood, John M, Luke, Jason John, Bao, Riyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603348/
https://www.ncbi.nlm.nih.gov/pubmed/37857525
http://dx.doi.org/10.1136/jitc-2023-007567