Vaccination with post-translational modified, homocitrullinated peptides induces CD8 T-cell responses that mediate antitumor immunity

BACKGROUND: Post-translational modification of proteins has the potential to alter the ability of T cells to recognize major histocompatibility complex (MHC) class -I and class-II restricted antigens, thereby resulting in altered immune responses. One such modification is carbamylation (homocitrulli...

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Detalles Bibliográficos
Autores principales: Shah, Sabaria, Cook, Katherine W, Symonds, Peter, Weißer, Juliane, Skinner, Anne, Al Omari, Abdullah, Paston, Samantha J, Pike, Ian, Durrant, Lindy G, Brentville, Victoria A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603355/
https://www.ncbi.nlm.nih.gov/pubmed/37857526
http://dx.doi.org/10.1136/jitc-2023-006966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603355/
https://www.ncbi.nlm.nih.gov/pubmed/37857526
http://dx.doi.org/10.1136/jitc-2023-006966

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