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NetAllergen, a random forest model integrating MHC-II presentation propensity for improved allergenicity prediction

MOTIVATION: Allergy is a pathological immune reaction towards innocuous protein antigens. Although only a narrow fraction of plant or animal proteins induce allergy, atopic disorders affect millions of children and adults and cost billions in healthcare systems worldwide. In silico predictors can ai...

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Detalles Bibliográficos
Autores principales: Li, Yuchen, Sackett, Peter Wad, Nielsen, Morten, Barra, Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603389/
https://www.ncbi.nlm.nih.gov/pubmed/37901344
http://dx.doi.org/10.1093/bioadv/vbad151