Targeting of STAT5 using the small molecule topotecan hydrochloride suppresses acute myeloid leukemia progression

Acute myeloid leukemia (AML) is a common type of acute leukemia in adults and relapse is one of the main reasons for treatment failure. FLT3-ITD mutations are associated with poor prognosis, short disease-free progression survival and high relapse rates in patients with AML. STAT5 is activated by FL...

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Detalles Bibliográficos
Autores principales: Li, Jiahui, Tang, Bin, Miao, Ying, Li, Guihong, Sun, Zhenliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603551/
https://www.ncbi.nlm.nih.gov/pubmed/37830151
http://dx.doi.org/10.3892/or.2023.8645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603551/
https://www.ncbi.nlm.nih.gov/pubmed/37830151
http://dx.doi.org/10.3892/or.2023.8645

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