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PanKmer: k-mer-based and reference-free pangenome analysis

SUMMARY: Pangenomes are replacing single reference genomes as the definitive representation of DNA sequence within a species or clade. Pangenome analysis predominantly leverages graph-based methods that require computationally intensive multiple genome alignments, do not scale to highly complex euka...

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Detalles Bibliográficos
Autores principales: Aylward, Anthony J, Petrus, Semar, Mamerto, Allen, Hartwick, Nolan T, Michael, Todd P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603592/
https://www.ncbi.nlm.nih.gov/pubmed/37846049
http://dx.doi.org/10.1093/bioinformatics/btad621