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Measurement of the pK(a) Values of Organic Molecules in Aqueous–Organic Solvent Mixtures by (1)H NMR without External Calibrants

[Image: see text] Aqueous–organic solvent mixtures are commonly used for reactions or analyses, where the components of a system are insoluble in pure water. The acid dissociation constant is an important property to measure in these media as it determines the charge state, solubility, and reactivit...

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Detalles Bibliográficos
Autores principales: Wallace, Matthew, Abiama, Nduchi, Chipembere, Miranda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603606/
https://www.ncbi.nlm.nih.gov/pubmed/37830153
http://dx.doi.org/10.1021/acs.analchem.3c02771