Addressing Acid-Catalyzed Deamidation and the Solubility of Hydrophobic Peptides in Multi-Attribute Method Workflows

[Image: see text] Recently, we introduced an optimized and automated Multi-Attribute Method (MAM) workflow, which (a) significantly reduces the number of missed cleavages using an automated two-step digestion procedure and (b) dramatically reduces chromatographic peak tailing and carryover of hydrop...

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Detalles Bibliográficos
Autores principales: Kristensen, Dan B., Ørgaard, Martin, Sloth, Trine M., Comamala, Gerard, Jensen, Pernille F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603607/
https://www.ncbi.nlm.nih.gov/pubmed/37824441
http://dx.doi.org/10.1021/acs.analchem.3c02609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603607/
https://www.ncbi.nlm.nih.gov/pubmed/37824441
http://dx.doi.org/10.1021/acs.analchem.3c02609

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