Multi-Omic, Histopathologic, and Clinicopathologic Effects of Once-Weekly Oral Rapamycin in a Naturally Occurring Feline Model of Hypertrophic Cardiomyopathy: A Pilot Study

SIMPLE SUMMARY: Hypertrophic cardiomyopathy (HCM) is the single most common cardiomyopathy in cats with no available therapeutic options in the asymptomatic period of the disease. The mechanisms by which rapamycin may exert effects at the level of the heart muscle remains elusive. This pilot study i...

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Detalles Bibliográficos
Autores principales: Rivas, Victor N., Kaplan, Joanna L., Kennedy, Susan A., Fitzgerald, Stuart, Crofton, Amanda E., Farrell, Aisling, Grubb, Louise, Jauregui, Carina E., Grigorean, Gabriela, Choi, Eunju, Harris, Samantha P., Stern, Joshua A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603660/
https://www.ncbi.nlm.nih.gov/pubmed/37893908
http://dx.doi.org/10.3390/ani13203184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603660/
https://www.ncbi.nlm.nih.gov/pubmed/37893908
http://dx.doi.org/10.3390/ani13203184

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