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Multi-Omic, Histopathologic, and Clinicopathologic Effects of Once-Weekly Oral Rapamycin in a Naturally Occurring Feline Model of Hypertrophic Cardiomyopathy: A Pilot Study
SIMPLE SUMMARY: Hypertrophic cardiomyopathy (HCM) is the single most common cardiomyopathy in cats with no available therapeutic options in the asymptomatic period of the disease. The mechanisms by which rapamycin may exert effects at the level of the heart muscle remains elusive. This pilot study i...
Autores principales: | Rivas, Victor N., Kaplan, Joanna L., Kennedy, Susan A., Fitzgerald, Stuart, Crofton, Amanda E., Farrell, Aisling, Grubb, Louise, Jauregui, Carina E., Grigorean, Gabriela, Choi, Eunju, Harris, Samantha P., Stern, Joshua A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603660/ https://www.ncbi.nlm.nih.gov/pubmed/37893908 http://dx.doi.org/10.3390/ani13203184 |
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