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Rat Grimace Scale as a Method to Evaluate Animal Welfare, Nociception, and Quality of the Euthanasia Method of Wistar Rats

SIMPLE SUMMARY: This study aimed to evaluate the pain associated with six methods of euthanasia: pentobarbital, CO(2), decapitation, isoflurane, ketamine + xylazine, and ketamine + CO(2) in Wistar rats, by applying the Rat Grimace Scale (RGS), comparing the scores, and determining the method with th...

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Detalles Bibliográficos
Autores principales: Domínguez-Oliva, Adriana, Olmos-Hernández, Adriana, Hernández-Ávalos, Ismael, Lecona-Butrón, Hugo, Mora-Medina, Patricia, Mota-Rojas, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603718/
https://www.ncbi.nlm.nih.gov/pubmed/37893885
http://dx.doi.org/10.3390/ani13203161