METTL3-mediated m(6)A modification of HMGA2 mRNA promotes subretinal fibrosis and epithelial–mesenchymal transition

Subretinal fibrosis is a major cause of the poor visual prognosis for patients with neovascular age-related macular degeneration (nAMD). Myofibroblasts originated from retinal pigment epithelial (RPE) cells through epithelial–mesenchymal transition (EMT) contribute to the fibrosis formation. N(6)-Me...

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Detalles Bibliográficos
Autores principales: Wang, Yuwei, Chen, Yuhong, Liang, Jian, Jiang, Mei, Zhang, Ting, Wan, Xiaoling, Wu, Jiahui, Li, Xiaomeng, Chen, Jieqiong, Sun, Junran, Hu, Yifan, Huang, Peirong, Feng, Jingyang, Liu, Te, Sun, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603769/
https://www.ncbi.nlm.nih.gov/pubmed/36945110
http://dx.doi.org/10.1093/jmcb/mjad005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603769/
https://www.ncbi.nlm.nih.gov/pubmed/36945110
http://dx.doi.org/10.1093/jmcb/mjad005

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