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Development of Bedaquiline-Loaded SNEDDS Using Quality by Design (QbD) Approach to Improve Biopharmaceutical Attributes for the Management of Multidrug-Resistant Tuberculosis (MDR-TB)

Background: The ever-growing emergence of antibiotic resistance associated with tuberculosis (TB) has become a global challenge. In 2012, the USFDA gave expedited approval to bedaquiline (BDQ) as a new treatment for drug-resistant TB in adults when no other viable options are available. BDQ is a dia...

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Detalles Bibliográficos
Autores principales: Jahan, Rao Nargis, Khan, Zafar, Akhtar, Md. Sayeed, Ansari, Mohd Danish, Solanki, Pavitra, Ahmad, Farhan J., Aqil, Mohd, Sultana, Yasmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603879/
https://www.ncbi.nlm.nih.gov/pubmed/37887211
http://dx.doi.org/10.3390/antibiotics12101510