Temperature Upshifts in Mammalian Cell Culture: A Suitable Strategy for Biosimilar Monoclonal Antibodies?

Temperature downshifts are the gold standard when setting up control strategies for mammalian cell culture processes. These shifts are performed to prolong production phases and attain heightened levels of productivity. For the development of biosimilars, however, the bottleneck is in achieving a pr...

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Detalles Bibliográficos
Autores principales: Marschall, Lukas, Gottimukkala, Chitti Babu, Kayal, Biswajit, Veeraraghavan, Veerabhadra Madurai, Mandal, Samir Kumar, Bandyopadhyay, Suman, Herwig, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603922/
https://www.ncbi.nlm.nih.gov/pubmed/37892879
http://dx.doi.org/10.3390/bioengineering10101149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603922/
https://www.ncbi.nlm.nih.gov/pubmed/37892879
http://dx.doi.org/10.3390/bioengineering10101149

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