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Behavioral Effects and Analgesic Profile of Hemoglobin-Derived Valorphin and Its Synthetic Analog in Rodents

Valorphin (V1) is a naturally occurring peptide derived from hemoglobin that has been found to have an affinity for opioid receptors and exhibits antinociceptive and anticonvulsant activity. Some of its synthetic analogs containing an aminophosphonate moiety show structure-dependent potent antinocic...

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Detalles Bibliográficos
Autores principales: Todorov, Petar, Assenov, Borislav, Angelov, Dimo, Dzhambazova, Elena, Pechlivanova, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603931/
https://www.ncbi.nlm.nih.gov/pubmed/37893157
http://dx.doi.org/10.3390/biomedicines11102783