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Preventive Action of Beta-Carotene against the Indoxyl Sulfate-Induced Renal Dysfunction in Male Adult Zebrafish via Regulations of Mitochondrial Inflammatory and β-Carotene Oxygenase-2 Actions

Indoxyl sulfate (IS) is a metabolic byproduct of indole metabolism. IS readily interacts with the mitochondrial redox metabolism, leading to altered renal function. The β-carotene oxygenase-2 (BCO2) enzyme converts carotenoids to intermediate products. However, the role of β-carotene (BC) in IS-indu...

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Detalles Bibliográficos
Autores principales: Muthuraman, Arunachalam, Sayem, Abu Sadat Md., Meenakshisundaram, Sakthiganapathi, Ali, Nemat, Ahmad, Sheikh F., AlAsmari, Abdullah F., Nishat, Shamama, Lim, Khian Giap, Paramaswaran, Yamunna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10603961/
https://www.ncbi.nlm.nih.gov/pubmed/37893028
http://dx.doi.org/10.3390/biomedicines11102654