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Deep Learning-Predicted Dihydroartemisinin Rescues Osteoporosis by Maintaining Mesenchymal Stem Cell Stemness through Activating Histone 3 Lys 9 Acetylation

[Image: see text] Maintaining the stemness of bone marrow mesenchymal stem cells (BMMSCs) is crucial for bone homeostasis and regeneration. However, in vitro expansion and bone diseases impair BMMSC stemness, limiting its functionality in bone tissue engineering. Using a deep learning-based efficacy...

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Detalles Bibliográficos
Autores principales: Wang, Ruoxi, Wang, Yu, Niu, Yuting, He, Danqing, Jin, Shanshan, Li, Zixin, Zhu, Lisha, Chen, Liyuan, Wu, Xiaolan, Ding, Chengye, Wu, Tianhao, Shi, Xinmeng, Zhang, He, Li, Chang, Wang, Xin, Xie, Zhengwei, Li, Weiran, Liu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604014/
https://www.ncbi.nlm.nih.gov/pubmed/37901168
http://dx.doi.org/10.1021/acscentsci.3c00794