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Deep Learning-Predicted Dihydroartemisinin Rescues Osteoporosis by Maintaining Mesenchymal Stem Cell Stemness through Activating Histone 3 Lys 9 Acetylation
[Image: see text] Maintaining the stemness of bone marrow mesenchymal stem cells (BMMSCs) is crucial for bone homeostasis and regeneration. However, in vitro expansion and bone diseases impair BMMSC stemness, limiting its functionality in bone tissue engineering. Using a deep learning-based efficacy...
Autores principales: | Wang, Ruoxi, Wang, Yu, Niu, Yuting, He, Danqing, Jin, Shanshan, Li, Zixin, Zhu, Lisha, Chen, Liyuan, Wu, Xiaolan, Ding, Chengye, Wu, Tianhao, Shi, Xinmeng, Zhang, He, Li, Chang, Wang, Xin, Xie, Zhengwei, Li, Weiran, Liu, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604014/ https://www.ncbi.nlm.nih.gov/pubmed/37901168 http://dx.doi.org/10.1021/acscentsci.3c00794 |
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