A Mouse Model for the Rapid and Binomial Assessment of Putative WNT/β-Catenin Signalling Inhibitors

Specific signalling thresholds of the WNT/β-catenin pathway affect embryogenesis and tissue homeostasis in the adult, with mutations in this pathway frequently occurring in cancer. Excessive WNT/β-catenin activity inhibits murine anterior development associated with embryonic lethality and accounts...

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Detalles Bibliográficos
Autores principales: Tse, Janson, O’Keefe, Ryan, Rigopolous, Angela, Carli, Annalisa L. E., Waaler, Jo, Krauss, Stefan, Ernst, Matthias, Buchert, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604108/
https://www.ncbi.nlm.nih.gov/pubmed/37893093
http://dx.doi.org/10.3390/biomedicines11102719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604108/
https://www.ncbi.nlm.nih.gov/pubmed/37893093
http://dx.doi.org/10.3390/biomedicines11102719

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