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Extracellular Vesicles Derived from Osteogenic-Differentiated Human Bone Marrow-Derived Mesenchymal Cells Rescue Osteogenic Ability of Bone Marrow-Derived Mesenchymal Cells Impaired by Hypoxia

In orthopedics, musculoskeletal disorders, i.e., non-union of bone fractures or osteoporosis, can have common histories and symptoms related to pathological hypoxic conditions induced by aging, trauma or metabolic disorders. Here, we observed that hypoxic conditions (2% O(2)) suppressed the osteogen...

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Detalles Bibliográficos
Autores principales: Wang, Chenglong, Stöckl, Sabine, Pattappa, Girish, Schulz, Daniela, Hofmann, Korbinian, Ilic, Jovana, Reinders, Yvonne, Bauer, Richard J., Sickmann, Albert, Grässel, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604262/
https://www.ncbi.nlm.nih.gov/pubmed/37893177
http://dx.doi.org/10.3390/biomedicines11102804