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Extrapyramidal Side Effects with Chronic Atypical Antipsychotic Can Be Predicted by Labeling Pattern of FosB and phosphoThr(34)-DARPP-32 in Nucleus Accumbens

Extrapyramidal side effects (EPS) can be induced by neuroleptics that regulate the expression of transcription factor FosB and dopaminergic mediator DARPP-32 in the striatum. However, the long-term neurobiological changes in striatal projection neurons resulting from a cumulative dosage of typical a...

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Detalles Bibliográficos
Autores principales: Prieto, Sonia G., Almeida, Maria Camila, Silva, João C. S., Del-Bel, Elaine, Echeverry, Marcela B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604349/
https://www.ncbi.nlm.nih.gov/pubmed/37893051
http://dx.doi.org/10.3390/biomedicines11102677