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Allyl Isothiocyanate Suppresses the Proliferation in Oral Squamous Cell Carcinoma via Mediating the KDM8/CCNA1 Axis

The dysregulated expression of cyclin genes can lead to the uncontrolled proliferation of cancer cells. Histone demethylase Jumonji-C domain-containing protein 5 (KDM8, JMJD5) and cyclin A1 (CCNA1) are pivotal in cell cycle progression. A promising candidate for augmenting cancer treatment is Allyl...

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Detalles Bibliográficos
Autores principales: Hsieh, Cheng-Chih, Yang, Cheng-Yu, Peng, Bo, Ho, Sien-Lin, Tsao, Chang-Huei, Lin, Chih-Kung, Lin, Chun-Shu, Lin, Gu-Jiun, Lin, Heng-Yi, Huang, Hung-Chi, Chang, Szu-Chien, Sytwu, Huey-Kang, Chia, Wei-Tso, Chen, Yuan-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604360/
https://www.ncbi.nlm.nih.gov/pubmed/37893043
http://dx.doi.org/10.3390/biomedicines11102669