Identifying Potent Nonsense-Mediated mRNA Decay Inhibitors with a Novel Screening System

Nonsense-mediated mRNA decay (NMD) is a quality control mechanism that degrades mRNAs carrying a premature termination codon. Its inhibition, alone or in combination with other approaches, could be exploited to develop therapies for genetic diseases caused by a nonsense mutation. This, however, requ...

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Detalles Bibliográficos
Autores principales: Carrard, Julie, Ratajczak, Fiona, Elsens, Joséphine, Leroy, Catherine, Kong, Rebekah, Geoffroy, Lucie, Comte, Arnaud, Fournet, Guy, Joseph, Benoît, Li, Xiubin, Moebs-Sanchez, Sylvie, Lejeune, Fabrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604367/
https://www.ncbi.nlm.nih.gov/pubmed/37893174
http://dx.doi.org/10.3390/biomedicines11102801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604367/
https://www.ncbi.nlm.nih.gov/pubmed/37893174
http://dx.doi.org/10.3390/biomedicines11102801

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