TGF-β and SHH Regulate Pluripotent Stem Cell Differentiation into Brain Microvascular Endothelial Cells in Generating an In Vitro Blood–Brain Barrier Model

Blood–brain barrier (BBB) models are important tools for studying CNS drug delivery, brain development, and brain disease. In vitro BBB models have been obtained from animals and immortalized cell lines; however, brain microvascular endothelial cells (BMECs) derived from them have several limitation...

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Detalles Bibliográficos
Autores principales: Lee, Na Geum, Lim, Mi-Hee, Park, Jongjin, Jeung, In Cheul, Hwang, Byungtae, Lee, Jangwook, Park, Jong-Gil, Son, Mi-Young, Han, Baek Soo, Yoon, Sung-Jin, Lee, Seon-Jin, Park, Young-Jun, Kim, Jae Ho, Lee, Nam-Kyung, Lee, Sang Chul, Min, Jeong-Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604460/
https://www.ncbi.nlm.nih.gov/pubmed/37892862
http://dx.doi.org/10.3390/bioengineering10101132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604460/
https://www.ncbi.nlm.nih.gov/pubmed/37892862
http://dx.doi.org/10.3390/bioengineering10101132

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