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TGF-β and SHH Regulate Pluripotent Stem Cell Differentiation into Brain Microvascular Endothelial Cells in Generating an In Vitro Blood–Brain Barrier Model
Blood–brain barrier (BBB) models are important tools for studying CNS drug delivery, brain development, and brain disease. In vitro BBB models have been obtained from animals and immortalized cell lines; however, brain microvascular endothelial cells (BMECs) derived from them have several limitation...
Autores principales: | Lee, Na Geum, Lim, Mi-Hee, Park, Jongjin, Jeung, In Cheul, Hwang, Byungtae, Lee, Jangwook, Park, Jong-Gil, Son, Mi-Young, Han, Baek Soo, Yoon, Sung-Jin, Lee, Seon-Jin, Park, Young-Jun, Kim, Jae Ho, Lee, Nam-Kyung, Lee, Sang Chul, Min, Jeong-Ki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604460/ https://www.ncbi.nlm.nih.gov/pubmed/37892862 http://dx.doi.org/10.3390/bioengineering10101132 |
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