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The Effects of Lipids on α-Synuclein Aggregation In Vitro

The small neuronal protein α-synuclein (αS) is found in pre-synaptic terminals and plays a role in vesicle recycling and neurotransmission. Fibrillar aggregates of αS are the hallmark of Parkinson’s disease and related neurodegenerative disorders. In both health and disease, interactions with lipids...

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Detalles Bibliográficos
Autores principales: Ramirez, Jennifer, Pancoe, Samantha X., Rhoades, Elizabeth, Petersson, E. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604467/
https://www.ncbi.nlm.nih.gov/pubmed/37892158
http://dx.doi.org/10.3390/biom13101476