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Minimal Residual Disease Detected by the 7NB-mRNAs ddPCR Assay Is Associated with Disease Progression in High-Risk Neuroblastoma Patients: A Prospective Multicenter Observational Study in Japan

SIMPLE SUMMARY: Neuroblastoma (NB) is a common pediatric tumor, and less than 50% of children with high-risk (HR)-NB can achieve long-term survival. This is mainly due to a tumor relapse caused by the activation of therapy-resistant minimal residual disease (MRD). Several assays measuring different...

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Detalles Bibliográficos
Autores principales: Nishimura, Noriyuki, Ishida, Toshiaki, Yokota, Isao, Matsumoto, Kimikazu, Shichino, Hiroyuki, Fujisaki, Hiroyuki, Sarashina, Takeo, Kamijo, Takehiko, Takimoto, Tetsuya, Iehara, Tomoko, Tajiri, Tatsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604505/
https://www.ncbi.nlm.nih.gov/pubmed/37887060
http://dx.doi.org/10.3390/biology12101350