Paraoxonase 2 Deficiency Causes Mitochondrial Dysfunction in Retinal Pigment Epithelial Cells and Retinal Degeneration in Mice

Although AMD is a complex disease, oxidative stress is a crucial contributor to its development, especially in view of the higher oxygen demand of the retina. Paraoxonase 2 (PON2) is a ubiquitously and constitutively expressed antioxidant protein that is found intracellularly associated with mitocho...

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Detalles Bibliográficos
Autores principales: Sreekumar, Parameswaran Gangadharan, Su, Feng, Spee, Christine, Hong, Elise, Komirisetty, Ravikiran, Araujo, Eduardo, Nusinowitz, Steven, Reddy, Srinivasa T., Kannan, Ram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604559/
https://www.ncbi.nlm.nih.gov/pubmed/37891899
http://dx.doi.org/10.3390/antiox12101820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604559/
https://www.ncbi.nlm.nih.gov/pubmed/37891899
http://dx.doi.org/10.3390/antiox12101820

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