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TCR-Engineered Lymphocytes Targeting NY-ESO-1: In Vitro Assessment of Cytotoxicity against Tumors

Adoptive T-cell therapies tailored for the treatment of solid tumors encounter intricate challenges, necessitating the meticulous selection of specific target antigens and the engineering of highly specific T-cell receptors (TCRs). This study delves into the cytotoxicity and functional characteristi...

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Detalles Bibliográficos
Autores principales: Alsalloum, Alaa, Alrhmoun, Saleh, Shevchenko, Julia, Fisher, Marina, Philippova, Julia, Perik-Zavodskii, Roman, Perik-Zavodskaia, Olga, Lopatnikova, Julia, Kurilin, Vasily, Volynets, Marina, Akahori, Yasushi, Shiku, Hiroshi, Silkov, Alexander, Sennikov, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604587/
https://www.ncbi.nlm.nih.gov/pubmed/37893178
http://dx.doi.org/10.3390/biomedicines11102805