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USP39-Mediated Non-Proteolytic Control of ETS2 Suppresses Nuclear Localization and Activity

ETS2 is a member of the ETS family of transcription factors and has been implicated in the regulation of cell proliferation, differentiation, apoptosis, and tumorigenesis. The aberrant activation of ETS2 is associated with various human cancers, highlighting its importance as a therapeutic target. U...

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Detalles Bibliográficos
Autores principales: Choi, Yunsik, Lee, Yuri, Kim, Jin Seo, Zhang, Peijing, Kim, Jongchan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604658/
https://www.ncbi.nlm.nih.gov/pubmed/37892157
http://dx.doi.org/10.3390/biom13101475