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Dopaminergic Input Regulates the Sensitivity of Indirect Pathway Striatal Spiny Neurons to Brain-Derived Neurotrophic Factor

SIMPLE SUMMARY: Motor dysfunction is among the main symptoms of Parkinson’s disease (PD). This is closely linked to the loss of the neurotransmitter dopamine (DA) in the midbrain and in the striatum. Additionally, the ability of striatal neurons to undergo adaptive cellular alterations and synaptic...

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Detalles Bibliográficos
Autores principales: Ayon-Olivas, Maurilyn, Wolf, Daniel, Andreska, Thomas, Granado, Noelia, Lüningschrör, Patrick, Ip, Chi Wang, Moratalla, Rosario, Sendtner, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604681/
https://www.ncbi.nlm.nih.gov/pubmed/37887070
http://dx.doi.org/10.3390/biology12101360