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Systematic analysis of integrated bioinformatics to identify upregulated THBS2 expression in colorectal cancer cells inhibiting tumour immunity through the HIF1A/Lactic Acid/GPR132 pathway

BACKGROUND: THBS2, a member of the extracellular matrix glycoprotein family, can effectively inhibit tumour growth and angiogenesis. This study aimed to investigate the biological role of THBS2 in various types of cancers and the mechanisms underlying the malignant progression of colorectal cancer (...

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Detalles Bibliográficos
Autores principales: Liu, Ye, Jiang, Chunhui, Xu, Chunjie, Gu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604812/
https://www.ncbi.nlm.nih.gov/pubmed/37884956
http://dx.doi.org/10.1186/s12935-023-03103-5