Oocyte-Specific Deletion of Slc6a9 Encoding the GLYT1 Glycine Transporter Eliminates Glycine Transport in Mouse Preimplantation Embryos and Their Ability to Counter Hypertonic Stress

Early preimplantation mouse embryos are sensitive to increased osmolarity, which can block their development. To overcome this, they accumulate organic osmolytes to maintain cell volume. The main organic osmolyte used by early mouse embryos is glycine. Glycine is transported during the mature egg an...

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Detalles Bibliográficos
Autores principales: Tscherner, Allison K., McClatchie, Taylor, Kaboba, Gracia, Boison, Detlev, Baltz, Jay M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604916/
https://www.ncbi.nlm.nih.gov/pubmed/37887344
http://dx.doi.org/10.3390/cells12202500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604916/
https://www.ncbi.nlm.nih.gov/pubmed/37887344
http://dx.doi.org/10.3390/cells12202500

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