cccDNA-Targeted Drug Screen Reveals a Class of Antihistamines as Suppressors of HBV Genome Levels

Chronic infection with hepatitis B virus (HBV) is incurable, as the current therapeutics cannot eliminate its persistent genomic material, cccDNA. Screening systems for cccDNA-targeting therapeutics are unavailable, as low copies of cccDNA in vitro complicate detection. To address this, cccDNA copie...

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Detalles Bibliográficos
Autores principales: Ren, Ee Chee, Zhuo, Nicole Ziyi, Goh, Zhi Yi, Bonne, Isabelle, Malleret, Benoît, Ko, Hui Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604930/
https://www.ncbi.nlm.nih.gov/pubmed/37892121
http://dx.doi.org/10.3390/biom13101438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604930/
https://www.ncbi.nlm.nih.gov/pubmed/37892121
http://dx.doi.org/10.3390/biom13101438

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