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Identification of BRCC3 and BRCA1 as Regulators of TAZ Stability and Activity

TAZ (WWTR1) is a transcriptional co-activator regulated by Hippo signaling, mechano-transduction, and G-protein couple receptors. Once activated, TAZ and its paralogue, YAP1, regulate gene expression programs promoting cell proliferation, survival, and differentiation, thus controlling embryonic dev...

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Detalles Bibliográficos
Autores principales: Sberna, Silvia, Lopez-Hernandez, Alejandro, Biancotto, Chiara, Motta, Luca, Andronache, Adrian, Verhoef, Lisette G. G. C., Caganova, Marieta, Campaner, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605050/
https://www.ncbi.nlm.nih.gov/pubmed/37887275
http://dx.doi.org/10.3390/cells12202431