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L-Type Amino Acid Transporter 1 (LAT1) Promotes PMA-Induced Cell Migration through mTORC2 Activation at the Lysosome

The mTOR signaling pathway integrates signaling inputs from nutrients, including glucose and amino acids, which are precisely regulated by transporters depending on nutrient levels. The L-type amino acid transporter 1 (LAT1) affects the activity of mTORC1 through upstream regulators that sense intra...

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Detalles Bibliográficos
Autores principales: Tae, Kun, Kim, Sun-Jick, Cho, Sang-Woo, Lee, Hoyeon, Cha, Hyo-Sun, Choi, Cheol-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605051/
https://www.ncbi.nlm.nih.gov/pubmed/37887348
http://dx.doi.org/10.3390/cells12202504