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L-Type Amino Acid Transporter 1 (LAT1) Promotes PMA-Induced Cell Migration through mTORC2 Activation at the Lysosome
The mTOR signaling pathway integrates signaling inputs from nutrients, including glucose and amino acids, which are precisely regulated by transporters depending on nutrient levels. The L-type amino acid transporter 1 (LAT1) affects the activity of mTORC1 through upstream regulators that sense intra...
Autores principales: | Tae, Kun, Kim, Sun-Jick, Cho, Sang-Woo, Lee, Hoyeon, Cha, Hyo-Sun, Choi, Cheol-Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605051/ https://www.ncbi.nlm.nih.gov/pubmed/37887348 http://dx.doi.org/10.3390/cells12202504 |
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