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ATP12A Proton Pump as an Emerging Therapeutic Target in Cystic Fibrosis and Other Respiratory Diseases

ATP12A encodes the catalytic subunit of the non-gastric proton pump, which is expressed in many epithelial tissues and mediates the secretion of protons in exchange for potassium ions. In the airways, ATP12A-dependent proton secretion contributes to complex mechanisms regulating the composition and...

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Detalles Bibliográficos
Autores principales: Dębczyński, Michał, Gorrieri, Giulia, Mojsak, Damian, Guida, Floriana, Zara, Federico, Scudieri, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605105/
https://www.ncbi.nlm.nih.gov/pubmed/37892136
http://dx.doi.org/10.3390/biom13101455