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Impact of cfDNA Reference Materials on Clinical Performance of Liquid Biopsy NGS Assays

SIMPLE SUMMARY: Liquid biopsy is a promising tool for the detection of low-frequency variants present in cancer and mosaic disease and is more and more adopted in clinical practice. Still, accurate validation and standardization across laboratories is lacking. Here, we show that the reference materi...

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Detalles Bibliográficos
Autores principales: Hallermayr, Ariane, Keßler, Thomas, Fujera, Moritz, Liesfeld, Ben, Bernstein, Samuel, von Ameln, Simon, Schanze, Denny, Steinke-Lange, Verena, Pickl, Julia M. A., Neuhann, Teresa M., Holinski-Feder, Elke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605119/
https://www.ncbi.nlm.nih.gov/pubmed/37894392
http://dx.doi.org/10.3390/cancers15205024