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DUBing Primary Tumors of the Central Nervous System: Regulatory Roles of Deubiquitinases

The ubiquitin proteasome system (UPS) utilizes an orchestrated enzymatic cascade of E1, E2, and E3 ligases to add single or multiple ubiquitin-like molecules as post-translational modification (PTM) to proteins. Ubiquitination can alter protein functions and/or mark ubiquitinated proteins for protea...

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Detalles Bibliográficos
Autores principales: Klonisch, Thomas, Logue, Susan E., Hombach-Klonisch, Sabine, Vriend, Jerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605193/
https://www.ncbi.nlm.nih.gov/pubmed/37892185
http://dx.doi.org/10.3390/biom13101503