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Ceramide synthase 4 overexpression exerts oncogenic properties in breast cancer

BACKGROUND: Ceramide, a bioactive signaling sphingolipid, has long been implicated in cancer. Members of the ceramide synthase (CerS) family determine the acyl chain lengths of ceramides, with ceramide synthase 4 (CerS4) primarily generating C18–C20-ceramide. Although CerS4 is known to be overexpres...

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Detalles Bibliográficos
Autores principales: Kim, Su-Jeong, Seo, Incheol, Kim, Min Hee, Park, Joo-Won, Kim, Shin, Park, Woo-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605224/
https://www.ncbi.nlm.nih.gov/pubmed/37885013
http://dx.doi.org/10.1186/s12944-023-01930-z