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The Role of Cyclin-Dependent Kinases (CDK) 4/6 in the Ovarian Tissue and the Possible Effects of Their Exogenous Inhibition

SIMPLE SUMMARY: CDK4/6 inhibitors combined with endocrine therapy are currently the standard of care for the treatment of patients with hormone-receptor-positive (HR+)/Human Epidermal Growth Factor Receptor 2-negative (HER2−) advanced breast cancer and those with high-risk early disease. Oncofertili...

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Detalles Bibliográficos
Autores principales: Scavone, Graziana, Ottonello, Silvia, Blondeaux, Eva, Arecco, Luca, Scaruffi, Paola, Stigliani, Sara, Cardinali, Barbara, Borea, Roberto, Paudice, Michele, Vellone, Valerio G., Condorelli, Margherita, Demeestere, Isabelle, Lambertini, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605229/
https://www.ncbi.nlm.nih.gov/pubmed/37894292
http://dx.doi.org/10.3390/cancers15204923