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Automated Image Analysis of Transmission Electron Micrographs: Nanoscale Evaluation of Radiation-Induced DNA Damage in the Context of Chromatin

Background: Heavy ion irradiation (IR) with high-linear energy transfer (LET) is characterized by a unique depth dose distribution and increased biological effectiveness. Following high-LET IR, localized energy deposition along the particle trajectories induces clustered DNA lesions, leading to low...

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Detalles Bibliográficos
Autores principales: Abd Al-razaq, Mutaz A., Isermann, Anna, Hecht, Markus, Rübe, Claudia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605235/
https://www.ncbi.nlm.nih.gov/pubmed/37887271
http://dx.doi.org/10.3390/cells12202427