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Nano-Architecture of Persistent Focal DNA Damage Regions in the Minipig Epidermis Weeks after Acute γ-Irradiation

Exposure to high acute doses of ionizing radiation (IR) can induce cutaneous radiation syndrome. Weeks after such radiation insults, keratinocyte nuclei of the epidermis exhibit persisting genomic lesions that present as focal accumulations of DNA double-strand break (DSB) damage marker proteins. Kn...

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Detalles Bibliográficos
Autores principales: Scherthan, Harry, Geiger, Beatrice, Ridinger, David, Müller, Jessica, Riccobono, Diane, Bestvater, Felix, Port, Matthias, Hausmann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605239/
https://www.ncbi.nlm.nih.gov/pubmed/37892200
http://dx.doi.org/10.3390/biom13101518