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Nano-Architecture of Persistent Focal DNA Damage Regions in the Minipig Epidermis Weeks after Acute γ-Irradiation
Exposure to high acute doses of ionizing radiation (IR) can induce cutaneous radiation syndrome. Weeks after such radiation insults, keratinocyte nuclei of the epidermis exhibit persisting genomic lesions that present as focal accumulations of DNA double-strand break (DSB) damage marker proteins. Kn...
Autores principales: | Scherthan, Harry, Geiger, Beatrice, Ridinger, David, Müller, Jessica, Riccobono, Diane, Bestvater, Felix, Port, Matthias, Hausmann, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605239/ https://www.ncbi.nlm.nih.gov/pubmed/37892200 http://dx.doi.org/10.3390/biom13101518 |
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