Gene Expression Analyses in Models of Rosiglitazone-Induced Physiological and Pathological Mineralization Identify Novel Targets to Improve Bone and Vascular Health

Clinical studies revealed detrimental skeletal and vascular effects of the insulin sensitizer rosiglitazone. We have shown earlier that rosiglitazone accelerates osteoblast differentiation from human mesenchymal stem cells (hMSC) at the expense of increased oxidative stress and cell death. In calcif...

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Detalles Bibliográficos
Autores principales: Bruedigam, Claudia, van Leeuwen, Johannes P. T. M., van de Peppel, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605243/
https://www.ncbi.nlm.nih.gov/pubmed/37887306
http://dx.doi.org/10.3390/cells12202462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605243/
https://www.ncbi.nlm.nih.gov/pubmed/37887306
http://dx.doi.org/10.3390/cells12202462

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