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Evening Primrose Extract Modulates TYMS Expression via SP1 Transcription Factor in Malignant Pleural Mesothelioma

SIMPLE SUMMARY: Malignant pleural mesothelioma belongs to the aggressive tumor of pleura commonly recognized at the advanced, chemoresistant stage. Thymidylate synthase (TYMS) is a critical therapeutic target because it determines the susceptibility to folate-related drug treatment. We have previous...

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Detalles Bibliográficos
Autores principales: Chmielewska-Kassassir, Małgorzata, Sobierajska, Katarzyna, Ciszewski, Wojciech M., Kryczka, Jakub, Zieleniak, Andrzej, Wozniak, Lucyna A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605291/
https://www.ncbi.nlm.nih.gov/pubmed/37894370
http://dx.doi.org/10.3390/cancers15205003