Proteome Analysis of Thyroid Hormone Transporter Mct8/Oatp1c1-Deficient Mice Reveals Novel Dysregulated Target Molecules Involved in Locomotor Function

Thyroid hormone (TH) transporter MCT8 deficiency causes severe locomotor disabilities likely due to insufficient TH transport across brain barriers and, consequently, compromised neural TH action. As an established animal model for this disease, Mct8/Oatp1c1 double knockout (DKO) mice exhibit strong...

Descripción completa

Detalles Bibliográficos
Autores principales: Siemes, Devon, Vancamp, Pieter, Markova, Boyka, Spangenberg, Philippa, Shevchuk, Olga, Siebels, Bente, Schlüter, Hartmut, Mayerl, Steffen, Heuer, Heike, Engel, Daniel Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605308/
https://www.ncbi.nlm.nih.gov/pubmed/37887331
http://dx.doi.org/10.3390/cells12202487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605308/
https://www.ncbi.nlm.nih.gov/pubmed/37887331
http://dx.doi.org/10.3390/cells12202487

Ejemplares similares