G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D(2) Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation

The D2 dopamine receptor (D2R) signals through both G proteins and β-arrestins to regulate important physiological processes, such as movement, reward circuitry, emotion, and cognition. β-arrestins are believed to interact with G protein-coupled receptors (GPCRs) at the phosphorylated C-terminal tai...

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Detalles Bibliográficos
Autores principales: Sánchez-Soto, Marta, Boldizsar, Noelia M., Schardien, Kayla A., Madaras, Nora S., Willette, Blair K. A., Inbody, Laura R., Dasaro, Christopher, Moritz, Amy E., Drube, Julia, Haider, Raphael S., Free, R. Benjamin, Hoffman, Carsten, Sibley, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605370/
https://www.ncbi.nlm.nih.gov/pubmed/37892234
http://dx.doi.org/10.3390/biom13101552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605370/
https://www.ncbi.nlm.nih.gov/pubmed/37892234
http://dx.doi.org/10.3390/biom13101552

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