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Development of a Single-Neurosphere Culture to Assess Radiation Toxicity and Pre-Clinical Cancer Combination Therapy Safety

SIMPLE SUMMARY: Exposure to radiation during nuclear catastrophes, natural sources such as space travel, or during cancer treatment can lead to central nervous system toxicity. The high sensitivity of neural progenitor cells (NPCs) to radiation poses a significant obstacle to dose escalation for the...

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Detalles Bibliográficos
Autores principales: Pathak, Bedika, Lange, Taylor E., Lampe, Kristin, Hollander, Ella, Oria, Marina, Murphy, Kendall P., Salomonis, Nathan, Sertorio, Mathieu, Oria, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605382/
https://www.ncbi.nlm.nih.gov/pubmed/37894283
http://dx.doi.org/10.3390/cancers15204916