Melatonin Reduces Aggravation of Renal Ischemia–Reperfusion Injury in Obese Rats by Maintaining Mitochondrial Homeostasis and Integrity through AMPK/PGC-1α/SIRT3/SOD2 Activation

This study examined the potential benefits of melatonin against renal ischemia and reperfusion (IR) injury in obesity and explored the underlying mechanisms. Obesity was induced in Wistar rats by feeding a high-fat diet for 16 weeks. Three obese groups that underwent renal IR induction (30-min renal...

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Detalles Bibliográficos
Autores principales: Kobroob, Anongporn, Kongkaew, Aphisek, Wongmekiat, Orawan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605397/
https://www.ncbi.nlm.nih.gov/pubmed/37886963
http://dx.doi.org/10.3390/cimb45100520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605397/
https://www.ncbi.nlm.nih.gov/pubmed/37886963
http://dx.doi.org/10.3390/cimb45100520

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